Reactive Perforating Collangenosis

Reactive Perforating Collangenosis

Reactive perforating collagenosis could be a terribly rare disease of the skin whereby there's Associate in Nursing elimination of altered supermolecule substance (called collagen) through the layer of skin (called epidermis). the 2 distinct kinds area unit Associate in Nursing heritable kind that manifests in childhood Associate in Nursingd an noninheritable form that happens in adulthood.

Only many cases are reported within the medical literature. At force, we've got had an opportunity to record, treat and document such a case. (One case isn't enough, though.)

It is additionally referred to as the haptic sensation of kidney failure, since it's terribly ordinarily seen in diabetic patients with kidney failure on prolonged chemical analysis.

The major abnormality is focal injury to scleroprotein followed by the elimination of the discontinuous scleroprotein through the stratum.

Cold or superficial trauma typically precipitates the lesions, particularly within the heritable kind. The noninheritable kind sometimes happens in patients with polygenic disorder or chronic kidney failure, particularly those receiving chemical analysis. noninheritable perforating collagenosis is additional common, occurring in as several as 100 percent of patients receiving maintenance dialysis.

The lesions area unit intensely fidgety, feat some scarring once resolution.

The heritable kind sometimes presents in infancy or time of life. The noninheritable kind happens in adults.

Small, well keratotic papules develop once minor trauma. The lesions begin as pin-sized lesions, and that they grow into larger papules over many weeks. They heal with residual minor scarring.

Intense haptic sensation could be a feature of noninheritable perforating collagenosis. during this condition, a history of polygenic disorder or kidney failure is usually evoked.

Flesh-colored, dome-shaped papules as massive as ten millimeter in diameter area unit typical. they need a keratinous plug. Lesions is also in a very linear pattern, exhibiting the Koebner development. Residual scarring is also seen from antecedently cured lesions. Lesions area unit most ordinarily found on the extensor muscle surfaces of the limbs and therefore the dorsa of the hands. Lesions can also occur on the trunk and therefore the face.

Acquired perforating collagenosis will occur in different nephropathies while not polygenic disorder.

Acquired perforating collagenosis has been reported in association with gland disease, adenosis, liver disfunction, lymphoma, and periampullary malignant neoplastic disease.

Homeopathic treatment

This is a rare sickness and our expertise is clearly restricted to 1 case that we've got treated at staring at it being a sort of scleroprotein sickness that medical care has smart treatment to supply, Reactive perforating collagenosis ought to notice smart management live. medical care is anticipated to experience the symptom, intense haptic sensation particularly and therefore the skin lesions. medical care is powerfully prompt.

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